재현성과 효율성을 보장하는 생산 전용 액체 크로마토그래피 시스템
생산 스케일 수준의 정제를 위해서는 반복적인 정제 조건 테스트가 필수적입니다. 따라서 간편하고, 효율적으로 그리고 정확하게 테스트를 수행할 수 있는 장비가 필요합니다. Cytiva(싸이티바)의 ÄKTA avant는 생산 스케일에 최적화 된 액체 크로마토그래피 시스템으로, 파워풀한 하드웨어와 수많은 정제 조건을 간편하게 디자인해주는 소프트웨어의 조합을 통해 최적의 생산 시스템을 구축할 수 있습니다.
- Column Logbook을 통해 Column 사용량, 성능을 주기적으로 확인 가능
- 빌트인 cooling-rack을 활용하여 안정적인 상태로 분취 샘플 보관
- Design of experiments(DoE)를 활용한 간편한 실험 디자인
- 목적에 맞는 최대 유속 선택 (25ml/min or 150ml/min)
Parameter | ÄKTA avant 25 |
---|---|
Application | Fast and secure process development and method optimization |
Buffer selection | 18 buffer inlets, option of up to 46 |
Compliance | The product fulfills valid directives and standards when used within the conditions specified in the user manual. The product must also be used in the same state as it was delivered from Cytiva and connected only to other CE labeled Cytiva modules or other products as recommended. For regulatory details please see declaration of conformity. |
Depth | 710 mm |
Flow cell path length | 2 mm (optional 10 mm) |
Flow rate | 0.001 mL/min-25 mL/min |
Height | 660 mm |
Multiple wavelength detection | Yes, up to 3 wavelengths |
Operating pressure (sample pump) max. | 10 MPa (100 bar, 1450 psi) |
Operating pressure max. | 20 MPa (200 bar, 2900 psi) |
Power consumption | 800 VA |
Protection class | IP 21, wet side IP 22 |
Pump type | Piston pump, metering type |
Relative humidity | 20% to 95% (non condensing) |
UV wavelength | 190–700 nm |
Viscosity | 0.35–10 cP (system pump), 0.7–10 cP (sample pump) |
Voltage | 100–120/220–240 VAC |
Width | 860 mm |
Application supported | Affinity chromatography, gel filtration/size exclusion chromatography, ion exchange chromatography, and hydrophobic interaction chromatography |
Safety certifications | 2006/42/EC (MD), 2004/108/EC (EMC), 1999/5/EC (R&TTE) |
Tubing i.d. (flow path) | 0.75 mm |
pH monitoring | 0–14 |
Automatic buffer preparation | BufferPro |
Autosampler injection | No |
Multiple sample injection | Yes, up to 7 samples |
Multistep purification | Yes (optional) |
Model | ÄKTA avant 25 |
Includes | Accessory box, 3 mixer chambers (0.6, 1.4 and 5 mL), pH electrode, fraction collector cassette tray, 2 deep-well cassettes, 2 cassettes for 50mL tubes |